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| TargetRank Output Description |
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Each 3' UTR is assigned a rank based on its TargetRank score. The 3' UTR with the highest score (predictive of greatest down-regulation in the presence of the siRNA/miRNA) is given a rank of 1. 3' UTRs with identical scores are given the same rank. The gene name for the corresponding Refseq (field links to the Entrez Gene database entry). Descriptive name for the corresponding Refseq. ID for the mRNA isoform scored by TargetRank. Score assigned by TargetRank to a Refseq's 3' UTR. See scoring description for details. Combind count of conserved and non-conserved 8mer, 7mer, and 6mer seed matches. Seed Matches perfectly conserved across aligned human, mouse, rat, and dog genomes. See genomes and UTRs for data sources. If multiple input sequences/miRNA names are provided and a seed match type is ambiguous (i.e. the same 3' UTR sequence can be interpreted as a different seed match type depending on which input siRNA/miRNA is considered), then all seed match types are assigned a value of 'NA'. See scoring description to find out how the TargetRank score is handled in such cases. Seed Matches with at least one nucleotide difference in one of the other three aligned genome regions (e.g. for a human seed match, at least one nucleotide difference in the aligned mouse, rat, or dog sequence). See genomes and UTRs for data sources. If multiple input sequences/miRNA names are provided and a seed match type is ambiguous (i.e. the same 3' UTR sequence can be interpreted as a different seed match type depending on which input siRNA/miRNA is considered), then all seed match types are assigned a value of 'NA'. See scoring description to find out how the TargetRank score is handled in such cases.
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