Supplementary data to:
Yeh, R.-F., Lim, L. P., and Burge, C. B. (2001) Computational
inference of homologous gene structures in the human genome. Genome Res. 11: 803-816.
The Banbury Cross site provides benchmark sequences for comparison of genefinding programs. Here are the results from running GenomeScan on the benchmark sequences:
GenomeScan was developed by Chris Burge in the Biology Department at MIT. The GenomeScan program and the model that underlies it are described in:
Yeh, R.-F., Lim, L. P., and Burge, C. B. (2001) Computational inference of homologous gene structures in the human genome. Genome Res. 11: 803-816.
GenomeScan is based in part on GENSCAN, described in:
Burge, C. and Karlin, S. (1997) Prediction of complete gene structures in human genomic DNA. J. Mol. Biol. 268, 78-94.
See also:
Burge, C. B. and Karlin, S. (1998) Finding the genes in genomic DNA.
Curr. Opin. Struct. Biol. 8, 346-354.