# README ############################################################################# # # # supplementary material to: # # SNP-based validation of exonic splicing enhancers, # by W.G. Faibrother, D.Holste, C.B.Burge, and P.A.Sharp # # # # 1.- DATA FILES # # RefSNP.ancestral.seq # - identifies ancestral allele in a set of coding region SNPs (build 112, NCBI) # # FORMAT # # rs# ancestral_allele 11mer#1 11mer#2 11mer(5'flank) 11mer(3'flank) allele#1 allele#2 # # # RefSNP.ancestral.freq.lst # - identifies the validate subset of SNPs # # # ESE57.lst # - rank-ordered list of ESEs by p-values, for the measure of relative risk (RR) # - data fields: # ESE_hexamer # average ESE_hexamer_counts in ancestral version of SNP dataset # RR # p_value # # # EXONS.snp # - exons that contain a validated SNPS # # # Last updated on: ...... Mon Dec 22 21:55:44 EST 2003 # questions to: ......... E-Mail: wgf3@mit.edu # # ################################################################################### #